DIPSS Myelofibrosis Score
Enter five clinical parameters to calculate the DIPSS score and estimate overall survival risk group in myelofibrosis.
Patient Parameters
Enter current clinical values to calculate the DIPSS score.
Score +1 if age > 65
Score +2 if < 10 g/dL
Score +1 if > 25 ×10⁹/L
Score +1 if ≥ 1%
Constitutional symptoms
Fever, night sweats, or weight loss > 10% in past year
Result
Enter patient values and press Calculate.
0
/ 6 pts
Risk Group
| Factor | Value | Points |
|---|
DIPSS Risk Scale
Low
Score 0
Median OS: not reached
Intermediate-1
Score 1–2
Median OS: ~14 years
Intermediate-2
Score 3–4
Median OS: ~4 years
High
Score 5–6
Median OS: ~18 months
For clinical use only. DIPSS is based on Passamonti et al., J Clin Oncol 2010. Always combine with full clinical assessment.
Summary
Enter five clinical parameters to calculate the DIPSS score and estimate overall survival risk group in myelofibrosis.
How it works
- Enter the patient's age (years) and check whether it is over 65.
- Enter the hemoglobin level (g/dL) — values below 10 g/dL score 2 points.
- Enter the white blood cell (WBC) count (×10⁹/L) — values above 25 score 1 point.
- Enter the circulating blast percentage — 1% or more scores 1 point.
- Indicate whether constitutional symptoms (fever, night sweats, weight loss >10% in 1 year) are present.
- The calculator sums all points and assigns a risk group with median overall survival estimate.
Use cases
- Stratify newly diagnosed myelofibrosis patients at any disease stage.
- Guide discussion of transplant eligibility and timing based on risk category.
- Support clinical decision-making for treatment intensification in intermediate or high-risk disease.
- Communicate prognosis to patients and caregivers in clear, standardized terms.
- Track prognostic category over time as disease parameters change.
Frequently Asked Questions
Last updated: 2026-07-23 ·
Reviewed by Nham Vu