HIV Risk Assessment

Select an exposure route to see CDC-estimated per-act HIV transmission probability and risk-reduction options.

Use the HIV Risk Assessment

Educational reference only. Data from CDC per-act transmission estimates. Figures are population averages — individual risk depends on viral load, STI status, and other factors. Not a substitute for HIV testing or clinical advice.

Select an exposure route

Exposure route

Per-act probability

Risk tier

Per-act probability (%)

Clinical context

Risk-reduction options

    Recent high-risk exposure? PEP (post-exposure prophylaxis) must be started within 72 hours. Go to an emergency room or urgent care clinic now.

    All routes at a glance

    Exposure route Per-act probability Tier
    Receptive anal intercourse (no condom) 1 in 72 highest
    Insertive anal intercourse (no condom) 1 in 909 high
    Receptive vaginal intercourse (no condom) 1 in 1,250 moderate
    Insertive vaginal intercourse (no condom) 1 in 2,500 moderate
    Receptive oral sex (fellatio) 1 in 10,000 low
    Sharing injection needles (IDU) 1 in 160 highest
    Needlestick injury (healthcare) 1 in 435 high
    Blood transfusion (untested blood) ~93 in 100 highest
    Mother-to-child (without intervention) ~1 in 4 highest
    Kissing / saliva contact Negligible negligible
    Casual / household contact Zero negligible

    Source: CDC.gov — HIV Transmission per-act risk estimates. "Negligible" and "Zero" routes have no documented transmission cases.

    Summary

    This tool presents CDC-published per-act HIV transmission probabilities for common exposure routes, from receptive anal intercourse to needle sharing and blood transfusion. Select a route to see the estimated risk figure, key biological factors that raise or lower that risk, and the prevention strategies (condoms, PrEP, treatment as prevention) that apply. All figures are educational estimates — they are not diagnostic and do not replace clinical evaluation.

    How it works

    1. Select the exposure route that applies to your situation.
    2. Review the CDC-estimated per-act transmission probability.
    3. Read the risk-reduction options shown for that route.
    4. Use the comparison table to see risk across all routes at once.
    5. Consult a healthcare provider for personal medical advice.

    Use cases

    • Understand relative transmission risk before speaking with a clinician.
    • Compare risk levels across different exposure types.
    • Learn which prevention methods apply to each route.
    • Support sexual-health education and counseling sessions.
    • Reference CDC probability data without navigating lengthy reports.
    • Inform decisions about PEP (post-exposure prophylaxis) urgency.

    Frequently Asked Questions

    Last updated: 2026-06-19 · Reviewed by Nham Vu