What does the TIMI score predict?

It predicts the 14-day composite rate of all-cause mortality, new or recurrent MI, and severe recurrent ischemia requiring urgent revascularization in patients with UA/NSTEMI.

What is considered high risk?

A score of 5-7 is generally considered high risk, corresponding to a 26-41% 14-day event rate. Scores of 3-4 are intermediate risk, and 0-2 are low risk.

What counts as "known coronary stenosis >= 50%"?

This refers to prior coronary angiography documenting at least one vessel with >= 50% luminal stenosis, or a prior history of coronary artery disease with documented obstruction.

What qualifies as "severe anginal symptoms"?

Two or more anginal events in the 24 hours prior to presentation counts as this criterion.

Is this tool a substitute for clinical judgment?

No. The TIMI score is a clinical decision support aid. It must be interpreted within the full clinical context by a qualified healthcare professional.

Does this apply to STEMI patients?

No. This calculator is for UA/NSTEMI only. A separate TIMI risk score exists for STEMI patients and uses different criteria.

TIMI Risk Score Calculator

Answer seven clinical yes/no questions to get the TIMI risk score (0-7) and 14-day major cardiac event probability for UA/NSTEMI patients.

Seven Clinical Criteria

Check every criterion that applies to the patient. Each checked item adds 1 point.

Age ≥ 65 years

Patient is 65 years old or older.

≥ 3 CAD risk factors

Family history of CAD, hypertension, hypercholesterolemia, diabetes, or active smoker.

Known coronary stenosis ≥ 50%

Prior angiography documenting at least one coronary artery with ≥ 50% luminal stenosis.

ST-segment deviation on ECG

ST deviation ≥ 0.5 mm on presenting electrocardiogram.

≥ 2 anginal events in prior 24 hours

Two or more episodes of angina at rest in the 24 hours before presentation.

Aspirin use in prior 7 days

Patient was taking aspirin within the 7 days prior to presentation (a marker of higher underlying risk).

Elevated serum cardiac markers

Elevated troponin I/T or CK-MB above the upper limit of normal.

TIMI Score Result

0 out of 7

Low Risk

14-Day Event Rate 4.7%

All-cause mortality, MI, or urgent revascularization.

Score	Risk	Event Rate
0–1	Low	4.7%
0–1	Low	4.7%
2	Low	8.3%
3	Intermediate	13.2%
4	Intermediate	19.9%
5	High	26.2%
6	High	40.9%
7	High	40.9%

For clinical decision support only. Always apply clinical judgment. Not a substitute for professional medical advice.

Summary

The TIMI (Thrombolysis in Myocardial Infarction) risk score is a validated seven-point scoring system used to stratify patients presenting with unstable angina (UA) or non-ST-elevation myocardial infarction (NSTEMI). Each of the seven binary criteria contributes one point, yielding a score from 0 to 7 that predicts the 14-day risk of death, new or recurrent MI, or urgent revascularization. Higher scores indicate greater risk and typically guide more aggressive management strategies.

How it works

Answer each of the seven yes/no clinical criteria.
Each "Yes" answer adds 1 point to the total score.
The tool sums the points and maps the score to a published risk category.
A 14-day major cardiac event rate derived from the original TIMI trial is displayed.
Use the result alongside clinical judgment to guide management decisions.

Use cases

Stratify UA/NSTEMI patients in the emergency department.
Determine whether a patient may benefit from early invasive strategy.
Support decisions about glycoprotein IIb/IIIa inhibitor therapy.
Quickly communicate risk level during handoffs.
Educate medical students on evidence-based ACS risk stratification.
Confirm manual score calculations at the bedside.

Frequently Asked Questions

Last updated: 2026-09-30 · Reviewed by Nham Vu