Is this the official MSKCC nomogram?

No. MSKCC uses dynamic multivariable formulas and additional inputs to predict continuous outcome probabilities. This calculator instead implements the published three-tier D’Amico classification. Use the official MSKCC website when an MSKCC nomogram result is required.

Is this tool a medical diagnosis?

No. This educational calculator only reproduces a categorical research classification and does not account for tumor volume, modern Grade Groups, imaging, biopsy details, or individual patient factors. Always consult a qualified urologist or oncologist for medical decisions.

What PSA value should I enter?

Enter your most recent pre-treatment PSA level in ng/mL as reported by your lab. Values measured after treatment (post-operative PSA) are not used for initial risk stratification.

What is the Gleason score?

The Gleason score is a grading system for prostate cancer based on how abnormal the tumor cells look under a microscope. It is the sum of the two most common patterns found (each graded 1–5). Scores range from 6 (low-grade) to 10 (high-grade).

What are clinical T stages?

Clinical T stage describes how far the tumor has spread within or beyond the prostate: T1 means clinically inapparent (not palpable), T2 means palpable but confined to the prostate, T3 means tumor has extended beyond the prostate capsule, and T4 means the tumor invades adjacent structures.

What does the risk group mean?

The D’Amico groups are broad categories originally developed to stratify biochemical outcome after local treatment. They are not an individualized survival probability and should not be used alone to choose treatment.

D’Amico Prostate Cancer Risk Group Calculator

Enter pretreatment PSA, biopsy Gleason score, and clinical T stage to calculate the original three-tier D’Amico risk group.

Clinical Inputs

Enter pre-treatment values from your pathology or lab report.

PSA Level (ng/mL)

Pre-treatment serum PSA in ng/mL.

Gleason Score (biopsy sum)

Clinical T Stage

Educational use only. This tool does not constitute medical advice. It reproduces the original D’Amico classification, not the official MSKCC nomogram, and cannot replace individual clinical assessment.

Enter your clinical values and click
Estimate Risk Group to see results.

Summary

This tool applies the original D’Amico criteria: low risk requires clinical T1–T2a, PSA at or below 10 ng/mL, and Gleason score at or below 6; intermediate risk is triggered by T2b, PSA above 10 through 20, or Gleason 7; high risk is triggered by T2c or higher, PSA above 20, or Gleason 8–10. It provides a broad educational category, not an MSKCC nomogram probability or medical advice.

How it works

Enter your pre-treatment PSA level in ng/mL.
Select your Gleason score from the biopsy report.
Choose your clinical T stage (extent of tumor spread).
The tool maps your inputs to the original D’Amico low, intermediate, or high risk criteria.
Review the estimated risk group and what it generally indicates.
Discuss results with your urologist or oncologist for clinical decisions.

Use cases

Understand how PSA, Gleason score, and clinical stage determine a D’Amico risk group.
Prepare informed questions before a prostate cancer consultation.
Cross-reference a pathology report against the published D’Amico criteria.
Educational review of how categorical prostate cancer risk stratification works.
Support patient self-education before or after a diagnosis discussion.

Frequently Asked Questions

Last updated: 2026-09-09 · Reviewed by Nham Vu

D’Amico Prostate Cancer Risk Group Calculator

Clinical Inputs

Inputs Used

Risk Factor Breakdown

Summary

How it works

Use cases

Frequently Asked Questions

D’Amico Prostate Cancer Risk Group Calculator

Use the D’Amico Prostate Cancer Risk Group Calculator

Clinical Inputs

Inputs Used

Risk Factor Breakdown

Summary

How it works

Use cases

Frequently Asked Questions