IPI Lymphoma Score
Enter five clinical factors to calculate the IPI score and five-year overall survival estimate for aggressive non-Hodgkin lymphoma.
For educational use only. Clinical decisions require evaluation by a qualified hematology/oncology specialist.
IPI Risk Factors
ECOG ≥ 2 = adverse factor (1 point)
> 1 extranodal site = adverse factor (1 point)
Select values on the left and click Calculate to see the IPI score and risk group.
IPI Risk Groups
| Score | Risk | 5-yr OS |
|---|---|---|
| 0–1 | Low | ~73% |
| 2 | Low-Intermediate | ~51% |
| 3 | High-Intermediate | ~43% |
| 4–5 | High | ~26% |
Summary
Enter five clinical factors to calculate the IPI score and five-year overall survival estimate for aggressive non-Hodgkin lymphoma.
How it works
- Enter the patient's age and select whether it exceeds 60 years.
- Indicate whether serum LDH is elevated above the institutional upper limit of normal.
- Select the ECOG performance status (0–4) — score ≥ 2 counts as an adverse factor.
- Choose the Ann Arbor stage — stage III or IV counts as an adverse factor.
- Enter the number of extranodal sites involved — more than one counts as an adverse factor.
- Click Calculate to see the IPI score, risk group, and five-year overall survival estimate.
Use cases
- Stratify newly diagnosed aggressive NHL patients into risk groups before treatment planning.
- Estimate five-year overall survival to guide goals-of-care conversations with patients and families.
- Support eligibility assessment for clinical trials that use IPI as an inclusion criterion.
- Benchmark individual patient risk against published cohort data.
- Educate medical students, residents, and oncology fellows on lymphoma prognostication.
- Communicate prognosis objectively between referring oncologists and tertiary hematology teams.
Frequently Asked Questions
Last updated: 2026-07-23 ·
Reviewed by Nham Vu