IPSS-R MDS Score
Enter five clinical parameters to calculate the IPSS-R score, risk category, and estimated median overall survival for MDS patients.
Use the IPSS-R MDS Score
Clinical Parameters
Must be <20% (values ≥20% indicate AML, not MDS)
Enter clinical parameters and click Calculate
Results appear here
Median Overall Survival
Population median from Greenberg et al. (Blood, 2012) — n=7,012
Subscale Breakdown
For educational and clinical reference only. Not a substitute for professional medical advice. Always interpret in the full clinical context.
Summary
The IPSS-R MDS Score calculator implements the Revised International Prognostic Scoring System published by Greenberg et al. (Blood, 2012). It combines five parameters — cytogenetic risk group, bone marrow blast percentage, hemoglobin, platelet count, and ANC — into a weighted total score. The score maps to five risk categories (Very Low through Very High) each with a published median overall survival derived from a 7,012-patient international database.
How it works
- Each parameter is mapped to a subscale score using the published IPSS-R weighting table.
- The five subscale scores are summed to produce the total IPSS-R score.
- The total score is mapped to one of five risk categories with corresponding median overall survival estimates.
Use cases
- Estimate prognosis for newly diagnosed MDS patients.
- Guide treatment decisions — watch-and-wait vs. transplant evaluation.
- Communicate risk category to patients and families.
- Determine appropriate clinical trial eligibility criteria.
- Track risk reclassification after re-biopsy.