FFP Dose Calculator

Enter patient weight and dosing target to calculate total FFP volume (mL) and approximate number of units needed for coagulation factor replacement.

Patient & Dosing Parameters

Enter weight and dosing target to calculate FFP volume and units.

mL/kg
10 — conservative 15 — aggressive

Standard is 250 mL. Confirm with your blood bank.

Enter patient weight and click Calculate to see results.

FFP Dosing Reference

Dose Context
10 mL/kg Mild coagulopathy; initial or maintenance dosing
12–13 mL/kg Moderate INR elevation or active bleeding
15 mL/kg Severe coagulopathy; massive transfusion protocol
1 unit ~200–280 mL per bag (institution-dependent)

For educational reference only. Dosing decisions must be guided by laboratory values, clinical context, and institutional protocols.

Summary

Enter patient weight and dosing target to calculate total FFP volume (mL) and approximate number of units needed for coagulation factor replacement.

How it works

  1. Enter the patient weight in kilograms or pounds (automatic conversion applies).
  2. Select or type a dosing target between 10 and 15 mL/kg — 10 mL/kg is a conservative starting dose; 15 mL/kg provides more aggressive factor replacement.
  3. Enter the volume per FFP unit (default 250 mL; adjust if your blood bank uses a different standard).
  4. The calculator multiplies weight (kg) by the dose to get total volume in mL.
  5. It then divides total volume by mL per unit and rounds up to the nearest whole unit.
  6. Review the summary and share with the clinical team or transfusion service.

Use cases

  • Calculating FFP dose for warfarin reversal prior to urgent surgery.
  • Estimating plasma units needed in a massive transfusion protocol (MTP).
  • Dosing FFP for patients with liver failure and coagulopathy.
  • Guiding FFP orders in DIC management.
  • Teaching medical students and residents how to calculate transfusion doses.
  • Cross-checking bedside dosing calculations in the emergency department.

Frequently Asked Questions

Last updated: 2026-07-23 · Reviewed by Nham Vu