Cryoprecipitate Dose Calculator

Enter patient weight, current fibrinogen, and target fibrinogen to calculate the number of cryoprecipitate units needed.

Patient Parameters

mg/dL
mg/dL

Common targets: 150–200 mg/dL (bleeding), ≥200 mg/dL (obstetric)

mg

Enter patient parameters and click
Calculate Dose to see results.

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Summary

Enter patient weight, current fibrinogen, and target fibrinogen to calculate the number of cryoprecipitate units needed.

How it works

  1. Enter the patient's weight in kilograms or pounds.
  2. Enter the current (measured) plasma fibrinogen in mg/dL.
  3. Enter the desired target fibrinogen in mg/dL.
  4. The calculator estimates plasma volume as weight (kg) × 45 mL/kg.
  5. Units = (Target − Current) × Plasma Volume (dL) ÷ 250 mg/unit.
  6. The result is rounded up to the nearest whole unit.

Use cases

  • Estimating cryoprecipitate dose in disseminated intravascular coagulation (DIC).
  • Fibrinogen replacement in massive transfusion protocols.
  • Pre-operative correction of hypofibrinogenemia before surgery.
  • Obstetric hemorrhage management when fibrinogen falls critically low.
  • Trauma resuscitation requiring coagulation factor replacement.
  • Clinical pharmacology education on blood product dosing.

Frequently Asked Questions

Last updated: 2026-07-22 · Reviewed by Nham Vu