Transferrin Saturation Calculator
Enter serum iron and TIBC values to instantly calculate transferrin saturation and interpret your iron status.
Use the Transferrin Saturation Calculator
Enter Lab Values
Normal range: 60–170 mcg/dL (10.7–30.4 umol/L)
Normal range: 250–370 mcg/dL (44.8–66.2 umol/L)
Reference Ranges
Iron Deficiency
< 20%
Normal
20% – 50%
Iron Overload / Overload Risk
> 50%
Reference ranges are general guidelines for adults. Always interpret results in clinical context with a qualified healthcare provider.
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Summary
Transferrin saturation (TSAT) expresses how much of the blood's iron-transport protein (transferrin) is currently carrying iron. It is calculated as serum iron divided by total iron-binding capacity (TIBC), multiplied by 100. Normal TSAT ranges from roughly 20% to 50%; values below 20% suggest iron deficiency, while values above 50% may indicate iron overload conditions such as hereditary hemochromatosis.
How it works
- Enter the serum iron value from your lab report.
- Enter the total iron-binding capacity (TIBC) value from the same panel.
- Select the unit your lab used — mcg/dL or umol/L.
- Click Calculate to see transferrin saturation percentage instantly.
- Review the interpretation banner for a clinical context of the result.
Use cases
- Screening for iron deficiency anemia when serum ferritin is ambiguous.
- Monitoring iron replacement therapy response over time.
- Initial assessment for hereditary hemochromatosis or iron overload.
- Evaluating iron status in chronic kidney disease patients.
- Checking iron availability in patients with anemia of chronic disease.
- Pre-surgical iron optimization planning.
Frequently Asked Questions
Last updated: 2026-05-28 · Reviewed by Nham Vu