NCCN Prostate Cancer Risk Calculator
Enter PSA, Gleason grade group, and clinical T stage to classify prostate cancer by NCCN risk group.
Patient Parameters
Optional — Very Low Criteria
Enter PSA, Gleason grade group, and T stage, then click Calculate.
NCCN Risk Group
Criteria Matched
NCCN Risk Group Reference
| Risk Group | PSA | GG | T Stage |
|---|---|---|---|
| Very Low | <10 & density <0.15 | GG 1 | T1c, <3 cores, ≤50%/core |
| Low | <10 | GG 1 | T1–T2a |
| Fav. Intermediate | 10–20 | GG 1–2 | T2b–T2c; 1 IR factor |
| Unfav. Intermediate | 10–20 | GG 1–3 | T2b–T2c; ≥2 IR factors or GG 3 |
| High | >20 | GG 4–5 | T3a |
| Very High | Any | Any | T3b–T4 |
Source: NCCN Clinical Practice Guidelines in Oncology — Prostate Cancer (2024). For educational use only.
Summary
Enter PSA, Gleason grade group, and clinical T stage to classify prostate cancer by NCCN risk group.
How it works
- Enter the pre-treatment PSA level in ng/mL.
- Select the Gleason grade group (GG 1 through GG 5) from the biopsy pathology report.
- Choose the clinical T stage (T1c through T4) from the DRE and imaging findings.
- Optionally enter the number of positive biopsy cores and PSA density for Very Low criteria.
- Click Calculate to see the NCCN risk group with the matching criteria and a brief management note.
Use cases
- Determine eligibility for active surveillance in very-low or low-risk disease.
- Identify intermediate-risk patients who may benefit from multimodal therapy.
- Flag high and very-high-risk cases that need early referral to radiation oncology or urology oncology.
- Educate patients on their risk category before discussing treatment options.
- Document standardized risk classification in clinical notes.
- Support multidisciplinary tumor board discussions.
- Help medical students and residents learn the NCCN criteria.
Frequently Asked Questions
Last updated: 2026-07-24 ·
Reviewed by Nham Vu