Multi-Step Synthesis Yield

Summary

In multi-step organic synthesis, each individual reaction step has its own percent yield. The overall yield of the entire sequence is the product of all individual step yields divided by 100 for each multiplication. This tool multiplies each step yield together to show you the running cumulative yield after every step and the final overall yield of the synthesis.

How it works

1. Enter the percent yield for each reaction step (1–100%).
2. Add up to 10 steps using the "Add Step" button.
3. The tool multiplies all step yields together to compute the cumulative yield at each stage.
4. The final overall yield is displayed prominently at the top.
5. Remove any step with the delete button; results update instantly.

Use cases

• Estimate the expected overall yield of a planned multi-step organic synthesis.
• Evaluate whether a synthetic route is viable based on cumulative yield losses.
• Compare different synthetic pathways by the final overall yield.
• Teach students how yield losses compound across multiple reaction steps.
• Quickly determine how many moles of starting material are needed given target product amount.

Frequently Asked Questions