SOFA Organ Failure Assessment

Enter baseline and current lab values for all 6 organ systems to calculate SOFA scores, compute delta-SOFA, and see which organs are deteriorating.

Use the SOFA Organ Failure Assessment

Educational use only. Not a substitute for clinical judgment. Interpret all scores alongside the full clinical picture.

Organ System Inputs

Baseline Current
1 Respiratory — PaO2/FiO2 (mmHg)
2 Coagulation — Platelets (×10³/μL)

Normal: 150–400 × 10³/μL

3 Liver — Total Bilirubin (mg/dL)

Normal: 0.1–1.2 mg/dL

4 Cardiovascular — MAP / Vasopressors
5 Neurological — Glasgow Coma Scale
6 Renal — Creatinine (mg/dL) and/or Urine Output (mL/day)

Baseline

Current

Higher of creatinine or urine output score is used. Normal creatinine: 0.6–1.2 mg/dL.

Enter baseline and current values,
then click Assess Organ Failure.

Summary

This tool calculates the Sequential Organ Failure Assessment (SOFA) score for six organ systems — respiratory, coagulation, liver, cardiovascular, neurological, and renal — and compares a baseline reading against the current values. The delta-SOFA (change from baseline) is the key metric in the Sepsis-3 definition: a SOFA increase of 2 or more points indicates life-threatening organ dysfunction in the setting of suspected infection. Serial SOFA tracking also guides ICU management and goals-of-care discussions.

How it works

  1. Enter baseline values for all 6 organ systems at ICU admission (or at the time of infection suspicion).
  2. Enter current values reflecting the patient's most recent lab results.
  3. The tool scores each organ system from 0 to 4 for both time points.
  4. Delta-SOFA is calculated as current total minus baseline total.
  5. Each organ's trajectory (stable, improving, or worsening) is displayed visually.
  6. An estimated ICU mortality range is shown based on the current total SOFA score.

Use cases

  • Apply the Sepsis-3 definition: delta-SOFA ≥ 2 in the setting of suspected infection confirms organ dysfunction due to sepsis.
  • Track ICU trajectory by comparing daily SOFA scores against admission baseline.
  • Identify which specific organ systems are driving deterioration.
  • Estimate mortality risk and support goals-of-care conversations.
  • Communicate serial organ dysfunction status between clinical teams.
  • Document organ function trajectory for quality-improvement audits.
  • Triage multiple ICU patients by current SOFA and delta-SOFA simultaneously.

Frequently Asked Questions

Last updated: 2026-06-11 · Reviewed by Nham Vu