What is the difference between Full and Partial Mayo Score?

The Full Mayo Score (0–12) includes all four subscores: stool frequency, rectal bleeding, endoscopic findings, and physician global assessment. The Partial Mayo Score (0–9) omits the endoscopic subscore, making it suitable for monitoring between colonoscopies.

What score defines clinical remission?

Clinical remission is typically defined as a Full Mayo Score of 0–2 with no individual subscore exceeding 1. Endoscopic remission requires an endoscopic subscore of 0 or 1.

How is disease severity classified?

For the Full Mayo Score: 0–2 = Remission, 3–5 = Mild, 6–10 = Moderate, 11–12 = Severe. For the Partial Mayo Score: 0–1 = Remission, 2–4 = Mild, 5–6 = Moderate, 7–9 = Severe.

Is this calculator a substitute for clinical judgment?

No. The Mayo Score is a validated clinical tool to support — not replace — physician assessment. Always interpret scores in the full clinical context and consult current gastroenterology guidelines.

What is the normal stool frequency baseline?

The stool frequency subscore is relative to the patient's normal: 0 = no increase, 1 = 1–2 stools/day above normal, 2 = 3–4 stools/day above normal, 3 = 5 or more stools/day above normal.

Can I use the Partial Mayo Score for clinical trials?

Some trials accept the Partial Mayo Score for screening or as a secondary endpoint, but most pivotal UC trials require the Full Mayo Score including endoscopy for primary endpoints. Check the specific trial protocol.

Mayo UC Score Calculator — Ulcerative Colitis

Summary

Calculate the Full or Partial Mayo Score to assess Ulcerative Colitis disease activity for clinical decision-making and trial eligibility.

How it works

Select the stool frequency score (0–3) based on the number of stools above normal per day.
Select the rectal bleeding score (0–3) based on daily blood in stool.
Select the physician global assessment (0–3) reflecting overall disease severity.
For the Full Mayo Score, also select the endoscopic findings score (0–3) from recent colonoscopy.
Click Calculate to see your Full and/or Partial Mayo Score with severity interpretation.

Use cases

Assess UC disease activity before initiating or changing therapy.
Determine clinical remission (Full Mayo Score ≤ 2, no subscore > 1).
Screen patients for eligibility in UC clinical trials.
Monitor response to induction therapy without repeat endoscopy using the Partial Mayo Score.
Document disease severity for specialist referral letters.
Track longitudinal disease activity over clinic visits.

Mayo UC Score Calculator

Score Inputs

Partial Mayo Score

Full Mayo Score

Subscore Breakdown