eGFR Dose Adjustment for Eye Medications
Enter age, sex, and serum creatinine to calculate CKD-EPI eGFR and get per-drug dose guidance for carbonic anhydrase inhibitors and other renal-cleared ophthalmic agents.
Patient Parameters
Uses CKD-EPI 2021 (race-free). Drug thresholds reflect current prescribing information and nephropharmacology literature.
Enter patient parameters and click Calculate to see eGFR and drug recommendations.
CKD-EPI 2021 eGFR
mL/min/1.73 m²
01530456090+
Ophthalmic Drug Dose Guidance
Clinical use only — not a substitute for prescribing references. Confirm with Lexicomp, Micromedex, or clinical pharmacy before prescribing. Thresholds shown are derived from approved labeling and nephropharmacology literature as of 2025.
Summary
Enter age, sex, and serum creatinine to calculate CKD-EPI eGFR and get per-drug dose guidance for carbonic anhydrase inhibitors and other renal-cleared ophthalmic agents.
How it works
- Enter the patient's age (18–100), biological sex, and serum creatinine (mg/dL or µmol/L).
- The tool applies the CKD-EPI 2021 race-free equation to compute eGFR (mL/min/1.73 m²).
- The calculated eGFR is matched against the threshold table for each ophthalmic drug.
- Each drug shows a color-coded status: use as normal, use with caution, reduce dose, or avoid.
- Review the recommendations alongside the patient's full medication list and clinical context.
Use cases
- Screen glaucoma patients with CKD before starting topical or systemic carbonic anhydrase inhibitors.
- Decide whether systemic acetazolamide is safe in a patient with reduced renal function.
- Check if dorzolamide or brinzolamide drops need any modification in stage 3–5 CKD.
- Educate patients with diabetes or hypertension about why kidney function affects their eye drops.
- Support pharmacist review of ophthalmic prescriptions in patients with nephrology co-management.
Frequently Asked Questions
Last updated: 2026-07-23 ·
Reviewed by Nham Vu