What score indicates high risk?

A Padua score of 4 or above is classified as high risk. In the Barbar et al. validation cohort, high-risk patients who did not receive prophylaxis had a VTE rate of 11.0% versus 0.3% in low-risk patients. Pharmacological prophylaxis is generally recommended for high-risk patients absent significant bleeding risk.

Which factors carry the most weight?

Active cancer, previous VTE (excluding superficial thrombosis), reduced mobility (bed rest ≥3 days), and known thrombophilic condition each contribute 3 points. All remaining factors contribute 1 point each.

Is this tool valid for surgical patients?

No. The Padua score was developed and validated for non-surgical hospitalized medical patients only. Surgical patients are typically assessed with the Caprini score or Rogers score.

What counts as "reduced mobility"?

Anticipated bed rest for at least 3 days due to patient limitation or a physician order. Patients who walk slowly or use a cane but are not restricted to bed do not qualify.

Padua VTE Prophylaxis Score

Select each applicable risk factor to calculate the Padua Prediction Score and determine whether pharmacological VTE prophylaxis is indicated.

Educational reference only. This tool does not replace clinical judgment. Prophylaxis decisions must weigh individual VTE and bleeding risk and remain the responsibility of the treating clinician. Always follow institutional protocols and applicable guidelines.

Summary

Select each applicable risk factor to calculate the Padua Prediction Score and determine whether pharmacological VTE prophylaxis is indicated.

How it works

Review each of the 11 risk factors and check every one that applies to the patient.
Each checked factor adds its assigned point value (1 or 3 points) to the running total.
The tool calculates the total score and classifies it as Low Risk (0–3) or High Risk (4+).
A prominent recommendation indicates whether pharmacological prophylaxis is suggested.
Use Reset to clear all selections and assess a new patient.

Use cases

Screen all admitted medical inpatients for VTE risk on the day of admission.
Support the decision to initiate LMWH, fondaparinux, or unfractionated heparin prophylaxis.
Identify low-risk patients where prophylaxis can safely be deferred.
Document structured VTE risk assessment in the medical record.
Educate medical students and residents on evidence-based VTE prevention.