Dilution CFU Calculator

Enter colony count, dilution factor, and plated volume to calculate the CFU/mL of your original sample.

Single Plate Calculation

Calculate CFU/mL from one plate count.

Spread plate = 0.1 mL  |  Pour plate = 1 mL

Multi-Plate Average

Average 2–4 plates from different dilutions (30–300 colony rule).

Fill in the fields on the left and click Calculate.

Serial Dilution Reference

Dilution steps (1:10 each) Dilution factor Decimal
110⁻¹0.1
210⁻²0.01
310⁻³0.001
410⁻⁴0.0001
510⁻⁵0.00001
610⁻⁶0.000001

Summary

Enter colony count, dilution factor, and plated volume to calculate the CFU/mL of your original sample.

How it works

  1. Enter the number of colonies counted on your agar plate.
  2. Enter the dilution factor used (e.g. 0.001 for a 10⁻³ dilution, or enter the exponent directly).
  3. Enter the volume plated in mL (typically 0.1 mL for spread plates or 1 mL for pour plates).
  4. The calculator applies the formula: CFU/mL = colonies ÷ (dilution factor × volume plated).
  5. Results are shown in CFU/mL and CFU/L, with scientific notation for large values.

Use cases

  • Determine bacterial load in a broth culture after serial dilution plating.
  • Quantify microbial contamination in food or water samples.
  • Calculate viable cell counts for inoculation in fermentation experiments.
  • Verify starter culture concentrations in dairy or beverage production.
  • Monitor growth curves by tracking CFU/mL over time during batch culture.
  • Assess antibiotic efficacy by comparing pre- and post-treatment plate counts.

Frequently Asked Questions

Last updated: 2026-07-01 · Reviewed by Nham Vu